Weijia Mao, Pei Wang, Lei Zhou, Dongxu Li, Xiangyang Li, Xin Lou, Xingxu Huang, Feng Wang, Yanli Zhang, Jianghuai Liu, Yongjie Wan. An upgraded nuclease prime editor platform enables high-efficiency singled or multiplexed knock-in/knockout of genes in mouse and sheep zygotes[J]. Protein&Cell. doi: 10.1093/procel/pwaf006